This post is part of our special coverage Syria Protests 2011/12.

Twitter is abuzz with news of the beginning of the end of the Assad regime, following a bomb explosion in Damascus in which three senior members of president Bashar Al Assad's inner circle were killed.

CNN's Arwa Damon reports:

@arwaCNN: free ‪#syria‬ army says attack was explosive device planted inside meeting room & triggered w/remote control

Emirati pundit Sultan Al Qassemi notes:

@SultanAlQassemi: Syrian Baathist child killing tyrants dropping like flies today.

Syrian blogger Yazan Badran is suspicious:

@yazanbadran: Something strange is going on. Is a solution finally being implemented? ‪#Syria‬ Either way, may they never rest in peace.

Syrian The 47th needs evidence:

@The47th: Just a question, anyone actually heard that specific explosion in Damas? friend I called in Rawda said he heard nothing.

BBC's Lina Sinjab tweets:

@BBCLinaSinjab: Residents very close 2 building said they haven't heard any sound of explosion or gunfire, haven't seen insured being removed either ‪#Syria

adding:

@BBCLinaSinjab: Just walked around national security building and saw no sign of explosions, no broken window, no heavy security presence ‪#Damascus‬ ‪#Syria

And Rafif Jouejati first asks:

@RafifJ: Internal elimination of potential defectors? ‪#Syria

Then announces:

@RafifJ: Regime is in total disarray. Go out NOW and protest, celebrate, sing songs, hoist Independence Flag, & shout: YALLA IR7AL YA BASHAR [Come on. Leave Bashar] ‪#Syria

And she adds:

@RafifJ: Get people out on a massive scale: IT'S HAPPENING! Don't look back on today 20 years from now and remember that you stayed silent. ‪#Syria

This video, posted by aldoghem on YouTube, shows celebrations on the streets of Damascus, following the attack:

Hiba Sarraj is waiting for news on a bigger target – Bashar Al Assad. She tweets [ar]:

Libyan Ismael has some advice:

@ChangeinLibya: Guys, if Syria|n State TV plays a documentary about taking care of your home & cooking, you should know it's over. @LibyanStateTV ‪#Libya

From Bahrain, Ali Al Saeed wonders:

@alialsaeed: Arabs either have psychopath generals or religious nut-jobs as leaders. There's no middle ground!?

And Jordanian Ali Hasani sums up the hash tags to follow on Twitter for this breaking news story:

@_AHA: Hashtags to follow what's going on: #Syria #DamascusBattle #Damascus #AssadEnd #AssadCountDown

This post is part of our special coverage Syria Protests 2011/12.